FOXA1 promotes tumor progression in prostate cancer via the insulin-like growth factor binding protein 3 pathway.

Fork-head box protein A1 (FOXA1) is a "pioneer factor" that is known NEEM TOOTHPASTE CINNAMINT to bind to the androgen receptor (AR) and regulate the transcription of AR-specific genes.However, the precise role of FOXA1 in prostate cancer (PC) remains unknown.In this study, we report that FOXA1 plays a critical role in PC cell proliferation.The exp

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Impact of massive deep-seated rock slope failures on mountain valley morphology in the northern Cottian Alps (NW Italy)

Deep-seated rock slope failures represent effective mechanisms of natural rock mass-wasting, able to radically change mountain-valley morphology.In the northern Cottian Alps, an extraordinary concentration Roasting Dish of instability phenomena occurs in extensive areas of the Susa and Chisone valleys.In the Main Map, at a scale of 1:30,000, a new

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